Nicotine is an alkaloid found in the nightshade family of plants (Solanaceae) that acts as a nicotinic acetylcholine agonist and a monoamine oxidase inhibitor. The biosynthesis takes place in the roots and accumulation occurs in the leaves of the Solanaceae. It constitutes approximately 0.6â€“3.0% of the dry weight of tobacco and is present in the range of 2â€“7 Âµg/kg of various edible plants.It functions as an antiherbivore chemical; therefore, nicotine was widely used as an insecticide in the past and nicotine analogs such as imidacloprid are currently widely used. In low doses (an average cigarette yields about 1 mg of absorbed nicotine), the substance acts as a stimulant in mammals, while high amounts (30â€“60 mg) can be fatal. This stimulant effect is the main factor responsible for the dependence-forming properties of tobacco smoking.
Nicotine Oral Films
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