Zolpidem oral films

Zolpidem oral films

Zolpidem oral films

Zolpidem is a prescription medication used for the treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic of the imidazopyridine class that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to GABAA receptors at the same location as benzodiazepines.It works quickly (usually within 15 minutes) and has a short half-life (two to three hours).

Zolpidem has not adequately demonstrated effectiveness in maintaining sleep (unless delivered in a controlled-release form); however, it is effective in initiating sleep.Its hypnotic effects are similar to those of the benzodiazepine class of drugs, but it is molecularly distinct from the classical benzodiazepine molecule and is classified as an imidazopyridine. Flumazenil, a benzodiazepine receptor antagonist, which is used for benzodiazepine overdose, can also reverse zolpidem's sedative/hypnotic and memory-impairing effects.

As an anticonvulsant and muscle relaxant, the drug's effects are not evident until dosages 10 and 20 times those required for sedation, respectively, are reached.For that reason, zolpidem has never been approved for either muscle relaxation or seizure prevention. Such drastically increased doses are also more inclined to induce one or more of the drug's adverse side effects, including hallucinations, sore throat, and amnesia.

Available Form:

Zolpidem Oral Films

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  • Validation and regulatory support.

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