Dextromethorphan HBr oral films

Dextromethorphan HBr oral films

Dextromethorphan HBr oral films

Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug.

It is one of the active ingredients in many over-the-counter cold and cough medicines, such as Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, and others, including generic labels. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.

DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist and the action of its major metabolite dextrorphan as an NMDA receptor antagonist, producing effects similar to those of the controlled substances ketamine and phencyclidine (PCP), as well as the active metabolite 3-methoxymorphinan which produces local anesthetic effects in rats with a potency above dextrorphan but below dextromethorphan itself.

Available Form:

Dextromethorphan HBR Films


Cough suppressant, Cold


Dextromethorphan 62.5 mg

Dextromethorphan 7.5 mg

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Systematic (IUPAC) Name
Chemical data
CAS number : 125-71-3
ATC code : R05DA09
PubChem : CID 15978238
DrugBank : APRD00655
ChemSpider : 13109865
KEGG : D03742
Formula : C18H25NO
Mol. mass : 271.4 g/mol

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